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If primary hypothyroidism was diagnosed, TSH levels are assessed every 4-6 weeks, and the dose of T4 is adjusted accordingly.

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Due to the long half-life of Levothyroxine, the peak therapeutic effect at a given dose of Levothyroxine sodium may not be attained for 4 to 6 weeks.

The low T4 dose such a person would receive is harmless, and Dr.

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Another potential area for additional research is whether it is helpful to modify the LT 4 dose because of residual signs and symptoms in a patient with a normal TSH, as long as the TSH remains within the goal reference range.

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There is an absence of qualitative research in the area of evaluating therapies for hypothyroidism, which raises questions about the validity of many of the quantitative instruments used in assessing patient well-being on various formulations and dosages.

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